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Statement
of
Interests
My
main interests are in how environmental information gets translated into
behavioral and reproductive responses and what role the neuroendocrine
system plays in the translation. I use amphibians as model systems.
Currently, projects in my laboratory include 1) studies on how
environmental contaminants may act as endocrine disruptors to affect
development and adult stress responses and behavior and 2) to
understand the interaction between the environment and molecular
mechanisms involved in seasonal reproduction in adults and sexual
differentiation during development. Specifically, we have been
investigating a very commonly used pesticide, endosulfan, and its effects
on reproduction and development in four different systems, tadpole
development, mosquitofish sexual dimorphism, salamander pheromone
production, and amphibian stress responses. We
have also investigated the effects of a common industrial compound on
sexual differentiation, and we are studying the complex physiological events that result
from exposure to environmental mixes of compounds found in
wastewater. Selected
Recent Publications from Our Lab: Park,
D, Hempleman, S.C., and Propper, C.R. 2001. Disrupted amphibian pheromone
systems in red-spotted newts: A potential causal factor in population
declines. Env. Health Perspect. 109: 669-674. Mayer,
L.P., Overstreet, S.L., Dyer,
C.D. and Propper, C.R. 2002. Sexually dimorphic expression of
steroidogenic factor 1 (SF-1) in developing gonads of the American
bullfrog, Rana catesbeiana. Gen.
Comp. Endocrinol. 127: 40-47. Park,
D. and Propper, C.R. 2002. Pheromones from female mosquitofish at
different stages of reproduction differentially affect male sexual
activity. Copeia 2002:1113-1117.
Park, D. and Propper, C.R. 2002.
Endosulfan affects male pheromonal detection and production in the
red-spotted newt. Bull. of
Env. Contamin. Toxicol. 69(4):609-16. Mayer,
L.P., Dyer, C.D. and Propper,
C.R. 2003. Exposure to 4-tert-octylphenol accelerates sexual
differentiation and disrupts expression of Steroidogenic Factor 1 (SF-1)
in developing bullfrogs. Env.
Health Persp. 111(4):557-61.
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