Diane M. Stearns  
Department of Chemistry and Biochemistry
Northern Arizona University
Stearns Home Page
Useful Chem and Tox Links
22. Coryell VH; Stearns DM.   Molecular analysis of hprt mutations induced by chromium picolinate in CHO AA8 cells. Mutation Research, 2006, in press.  (view pdf)
21.  Coryell VH; Stearns DM.  Molecular analysis of hprt mutations generated in Chinese hamster ovary EM9 cells by uranyl acetate, by hydrogen peroxide, and spontaneously.  Molecular Carcinogenesis 2006 45:60-72.   (view abstract)
20.  Stearns DM; Yazzie M; Bradley AS; Coryell VH; Shelley JT; Ashby A; Asplund CS; Lantz RC.  Uranyl acetate induces hprt mutations and uranium-DNA adducts in Chinese hamster ovary EM9 cells.  Mutagenesis 2005 20:417-423. (view pdf)
19.  Blankert SA; Coryell VH; Picard BT; Wolf KK; Lomas RE; Stearns DM. Characterization of nonmutagenic Cr(III)-DNA interactions. Chemical Research in Toxicology 2003 16:847-854. (view abstract)
18.  Yazzie M; Gamble SL; Civitello ER; Stearns DM. Uranyl acetate causes DNA single strand breaks in vitro in the presence of ascorbate (vitamin C).  Chemical Research in Toxicology 2003, 16: 524-530. (view abstract)
17.  Manygoats KR; Yazzie M; Stearns DM.  Ultrastructural damage in chromium picolinate-treated cells: a TEM study. Transmission electron microscopy.  Journal of Biological Inorganic Chemistry 2002, 7:791-798. (view pdf)
16.  Stearns DM; Silveira SM; Wolf KK; Luke AM.  Chromium picolinate is mutagenic at the hprt locus in Chinese hamster ovary cells.  Mutation Research 2002, 513:135-142. (view pdf)
15.  Civitello ER; Leniek RG; Hossler KA; Haebe K; Stearns DM.  Synthesis of peptide-oligonucleotide conjugates for chromium coordination.  Bioconjugate Chemistry 2001, 12:459-463. (view abstract)
14.  Sugden KD; Stearns DM.  The role of chromium(V) in the mechanism of chromate-induced oxidative DNA damage and cancer.  Journal of Environmental Pathology, Toxicology and Oncology 2000, 19:215-230.
13.  Stearns DM.  Is chromium a trace essential metal? Biofactors 2000, 11:149-162. (view abstract)
12.  Wise JP, Sr.; Stearns DM.  Chromium carcinogenicity: the roles of valence state and solubility.  The Occupational Environmental Medicine Report 1997, 11:100-103.
11.  Stearns DM; Wetterhahn KE.  Intermediates produced in the reaction of chromium(VI) with dehydroascorbate cause single-strand breaks in plasmid DNA.  Chemical Research in Toxicology 1997, 10:271-278. (view abstract)
10.  Stearns DM; BelBruno JJ; Wetterhahn KE.  A prediction of Cr(III) accumulation in humans from ingestion of Cr dietary supplements.  FASEB Journal 1995, 9:1650-1657. (This article can be retrieved from the FASEB Journal web page)
9.  Stearns DM; Wise JP; Patierno SR; Wetterhahn KE.  Chromium(III) picolinate produces chromosome damage in Chinese hamster ovary cells.  FASEB Journal 1995, 9:1643-1649. (This article can be retrieved from the FASEB Journal web page)
8.  Stearns DM; Courtney KD; Kennedy LJ; Giangrande PH; Phieffer LS; Wetterhahn KE.  Reduction of chromium(VI) by ascorbate leads to chromium-DNA binding and DNA strand breaks in vitro.  Biochemistry 1995, 34:910-919. (view abstract)
7.  Wise JP; Stearns DM; Wetterhahn KE; Patierno SR.  Cell-enhanced dissolution of carcinogenic lead chromate particles: the role of individual dissolution products in clastogenesis.  Carcinogenesis 1994, 15:2249-2254.
6.  Olin KL; Stearns DM; Armstrong WH; Keen CL.  Comparative retention/absorption of 51chromium (51Cr) from 51Cr chloride, 51Cr nicotinate, and 51Cr picolinate in a rat model.  Trace Elements and Electrolytes 1994, 11:182-186.
5.  Stearns DM; Courtney KD; Giangrande PH; Phieffer LS; Wetterhahn KE.  Chromium(VI) reduction by ascorbate:  role of reactive intermediates in DNA damage in vitro.  Environmental Health Perspectives 1994, 102 (Suppl. 3):21-25. (view html)
4.  Stearns DM; Wetterhahn KE.  Reaction of chromium(VI) with ascorbate produces chromium(V), chromium(IV) and carbon-based radicals.  Chemical Research in Toxicology 1994, 7:219-230. (view abstract)
3.  Stearns DM; Armstrong WH.  Mononuclear and binuclear chromium(III) picolinate complexes.  Inorganic Chemistry 1992, 31:5178-5184. (view abstract)
2.  Stearns DM; Hoffman LR; Armstrong WH.  Structure of N,N-[bis(2-pyridylmethyl)-g-aminobutyrato]copper(II) bromide methanol solvate.  Acta Crystallographica, Section C 1992, 48:253-256.
1.  Chambron JC; Eichhorn DM; Franczyk TS; Stearns DM.  Structure of (hydridotris-pyrazolylborato)(iodo)(methyl)(triphenylphosphino)rhodium(III).  Acta Crystallographica, Section C 1991, 47:1732-1734.
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